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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MYBL2
All Species:
21.82
Human Site:
S421
Identified Species:
36.92
UniProt:
P10244
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P10244
NP_002457.1
700
78764
S421
R
K
R
R
V
A
L
S
P
V
T
E
N
S
T
Chimpanzee
Pan troglodytes
XP_514658
769
86303
S421
R
K
R
R
V
A
L
S
P
V
T
E
N
S
T
Rhesus Macaque
Macaca mulatta
XP_001084853
700
78675
S421
R
K
R
R
V
A
L
S
P
V
T
E
N
S
T
Dog
Lupus familis
XP_534424
883
97262
S604
K
K
R
R
V
A
L
S
P
V
T
E
N
S
A
Cat
Felis silvestris
Mouse
Mus musculus
P48972
704
79084
S424
K
K
R
R
V
A
L
S
P
V
T
E
N
S
A
Rat
Rattus norvegicus
NP_001100006
704
79549
S425
K
K
R
R
V
A
L
S
P
V
T
E
N
S
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511778
753
85883
G457
K
K
R
R
I
R
V
G
H
S
P
V
S
D
H
Chicken
Gallus gallus
Q03237
686
77718
V404
R
K
I
S
L
S
P
V
T
E
N
A
P
S
T
Frog
Xenopus laevis
P52551
743
82891
A424
N
F
W
S
K
Q
D
A
L
E
L
E
N
P
S
Zebra Danio
Brachydanio rerio
NP_001003867
633
70853
L378
K
S
T
P
V
K
I
L
P
F
S
P
S
Q
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797351
686
76826
F427
T
P
I
K
T
L
P
F
S
P
S
Q
F
L
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P20024
340
36221
G85
E
A
I
I
R
L
H
G
L
L
G
N
K
W
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9S7G7
776
86488
L493
R
L
F
G
A
T
E
L
E
C
K
T
D
T
N
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
O13493
324
36522
A69
G
P
M
T
Q
E
E
A
A
I
I
V
R
E
V
Conservation
Percent
Protein Identity:
100
88
98.2
72.5
N.A.
85.2
87.7
N.A.
38.3
72.5
54.2
52.1
N.A.
N.A.
N.A.
N.A.
37.8
Protein Similarity:
100
89.7
98.7
74.7
N.A.
89.4
91.3
N.A.
54.5
81.5
69
65.8
N.A.
N.A.
N.A.
N.A.
54
P-Site Identity:
100
100
100
86.6
N.A.
86.6
86.6
N.A.
20
26.6
13.3
13.3
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
46.6
40
26.6
40
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
20.1
N.A.
25.5
N.A.
20.7
Protein Similarity:
N.A.
31.8
N.A.
40.8
N.A.
29.5
P-Site Identity:
N.A.
0
N.A.
6.6
N.A.
0
P-Site Similarity:
N.A.
13.3
N.A.
20
N.A.
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
8
43
0
15
8
0
0
8
0
0
22
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
8
0
0
0
0
0
8
8
0
% D
% Glu:
8
0
0
0
0
8
15
0
8
15
0
50
0
8
0
% E
% Phe:
0
8
8
0
0
0
0
8
0
8
0
0
8
0
8
% F
% Gly:
8
0
0
8
0
0
0
15
0
0
8
0
0
0
0
% G
% His:
0
0
0
0
0
0
8
0
8
0
0
0
0
0
8
% H
% Ile:
0
0
22
8
8
0
8
0
0
8
8
0
0
0
0
% I
% Lys:
36
58
0
8
8
8
0
0
0
0
8
0
8
0
0
% K
% Leu:
0
8
0
0
8
15
43
15
15
8
8
0
0
8
0
% L
% Met:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
0
0
0
0
0
8
8
50
0
15
% N
% Pro:
0
15
0
8
0
0
15
0
50
8
8
8
8
8
0
% P
% Gln:
0
0
0
0
8
8
0
0
0
0
0
8
0
8
0
% Q
% Arg:
36
0
50
50
8
8
0
0
0
0
0
0
8
0
0
% R
% Ser:
0
8
0
15
0
8
0
43
8
8
15
0
15
50
15
% S
% Thr:
8
0
8
8
8
8
0
0
8
0
43
8
0
8
29
% T
% Val:
0
0
0
0
50
0
8
8
0
43
0
15
0
0
8
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
0
0
0
8
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _